Lawrence J Stern Selected Research

HLA-DR1 Antigen (HLA DR1 Antigen)

10/2012	HLA-DM constrains epitope selection in the human CD4 T cell response to vaccinia virus by favoring the presentation of peptides with longer HLA-DM-mediated half-lives.
1/2012	Minimal conformational plasticity enables TCR cross-reactivity to different MHC class II heterodimers.
7/2009	Peptide immunotherapy in allergic asthma generates IL-10-dependent immunological tolerance associated with linked epitope suppression.
7/2008	Vaccinia peptides eluted from HLA-DR1 isolated from virus-infected cells are recognized by CD4+ T cells from a vaccinated donor.
7/2007	Human cytotoxic CD4+ T cells recognize HLA-DR1-restricted epitopes on vaccinia virus proteins A24R and D1R conserved among poxviruses.
9/2004	A hairpin turn in a class II MHC-bound peptide orients residues outside the binding groove for T cell recognition.
12/2002	Examination of the highly diverse CD4(+) T-cell repertoire directed against an influenza peptide: a step towards TCR proteomics.

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Lawrence J Stern Research Topics

Disease

8	Infections 01/2021 - 04/2004
7	Neoplasms (Cancer) 01/2022 - 01/2018
5	Human Influenza (Influenza) 01/2017 - 12/2002
4	Vaccinia 06/2013 - 10/2007
2	Narcolepsy 01/2020 - 11/2019
2	Inflammation (Inflammations) 01/2019 - 01/2019
2	Communicable Diseases (Infectious Diseases) 10/2012 - 01/2009
2	Malaria 01/2009 - 05/2006
2	Smallpox (Variola) 10/2007 - 07/2007
1	COVID-19 01/2022
1	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2021
1	Hyperglycemia 01/2021
1	Epstein-Barr Virus Infections 11/2019
1	Melanoma (Melanoma, Malignant) 08/2019
1	Autoimmune Diseases (Autoimmune Disease) 01/2019
1	Listeriosis (Listeria Infection) 01/2019
1	Neoplasm Metastasis (Metastasis) 01/2018
1	Juvenile Arthritis (Juvenile Idiopathic Arthritis) 02/2016
1	Hypersensitivity (Allergy) 05/2012
1	Muscular Dystrophies (Muscular Dystrophy) 05/2012
1	Encephalitis (Encephalitis, Rasmussen) 05/2012
1	Asthma (Bronchial Asthma) 07/2009
1	Transfusion Reaction 08/2007
1	Neonatal Alloimmune Thrombocytopenia 08/2007
1	Ectromelia (Phocomelia) 07/2007
1	Mpox (monkeypox) 07/2007
1	Cowpox 07/2007
1	Rheumatoid Arthritis 04/2006
1	Decompression Sickness (Bends) 09/2004

Drug/Important Bio-Agent (IBA)

16	Peptides (Polypeptides)IBA 01/2021 - 12/2002
9	EpitopesIBA 01/2022 - 05/2006
7	HLA-DR1 Antigen (HLA DR1 Antigen)IBA 10/2012 - 12/2002
5	Proteins (Proteins, Gene)FDA Link 01/2022 - 04/2004
4	Histocompatibility Antigens Class IIIBA 01/2021 - 07/2007
4	T-Lymphocyte Epitopes (Epitopes, T Lymphocyte)IBA 10/2012 - 07/2007
3	T-Cell Antigen Receptors (T-Cell Receptor)IBA 11/2019 - 09/2004
3	Subunit VaccinesIBA 01/2009 - 05/2006
3	VaccinesIBA 01/2009 - 07/2007
2	AminopeptidasesIBA 01/2021 - 08/2019
2	OrexinsIBA 01/2020 - 11/2019
2	AntigensIBA 11/2019 - 01/2012
2	LigandsIBA 01/2019 - 01/2019
2	Viral AntigensIBA 01/2018 - 06/2010
2	Pharmaceutical PreparationsIBA 01/2018 - 05/2012
2	Viral ProteinsIBA 06/2013 - 07/2008
2	Hemagglutinins (Hemagglutinin)IBA 01/2012 - 12/2002
1	HLA-DQ5 antigenIBA 01/2022
1	HLA-DPw4 antigenIBA 01/2022
1	EnzymesIBA 01/2022
1	mRNA VaccinesIBA 01/2022
1	ApolipoproteinsIBA 01/2021
1	Immunodominant EpitopesIBA 11/2019
1	Histocompatibility Antigens Class IIBA 08/2019
1	Immune Checkpoint InhibitorsIBA 08/2019
1	Phosphotransferases (Kinase)IBA 01/2019
1	tyrosine receptor (receptor, tyrosine)IBA 01/2019
1	AutoantigensIBA 01/2019
1	Glycoproteins (Glycoprotein)IBA 01/2019
1	Actin Depolymerizing Factors (Cofilins)IBA 11/2017
1	Serine Proteases (Serine Protease)IBA 11/2017
1	Prealbumin (Transthyretin)IBA 02/2016
1	Viral Core ProteinsIBA 10/2012
1	HLA-DR4 Antigen (HLA DR4 Antigen)IBA 01/2012
1	AllergensIBA 07/2009
1	Biomarkers (Surrogate Marker)IBA 07/2009
1	Human Immunodeficiency Virus ProteinsIBA 01/2007
1	B-Lymphocyte Epitopes (B-Cell Epitope)IBA 05/2006
1	GoldIBA 04/2006
1	polypeptide CIBA 09/2004
1	Interferon-gamma (Interferon, gamma)IBA 12/2002
1	peptide AIBA 12/2002

Therapy/Procedure

2	Immunotherapy 08/2019 - 07/2009
1	Highly Active Antiretroviral Therapy (HAART) 01/2007
1	Therapeutics 01/2007